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During the first year in the ACCESS program, students conduct research for one quarter in each of three different laboratories in order to gain exposure to diverse research environments. At the end of the Spring quarter, the student chooses one of these labs in which to complete the dissertation research. If the head of the laboratory is a member of the Department of Pathology and Laboratory Medicine, the student enters the Cellular and Molecular Pathology doctoral program. The student's subsequent course of study and progress is administered by the Department of Pathology and Laboratory Medicine from year two until the completion of the Ph.D. degree.
ACCESS Core Curriculum
Students must complete the core curriculum and have chosen a lab by end of summer of their first year.
Chemical and physical properties of proteins and nucleic acids. Structure, cloning, and analysis of DNA; biosynthesis and processing of RNA; biosynthesis, purification, structure, and analysis of proteins; correlation of structure and biological properties. Concurrently scheduled with course CM153G. Letter grading.
Basic concepts in modern genetics, with examples from both eukaryotic and prokaryotic systems. Emphasis on use of genetic techniques for addressing fundamental questions in cellular biochemistry. Topics include mutagenesis, repair, recombination, transposition, genetic regulation, developmental genetics, neurogenetics, and immunogenetics. Letter grading.
Cell cycle regulation; chromosomes and DNA repair; protein trafficking and endocytosis; extracellular matrix, cell to cell communication and signal transduction; cell transformation and apoptosis; molecular aspects of development, differentiation, and cancer. Concurrently scheduled with course CM169. Letter grading.
Elective survey courses covering various disciplines and topics are offered. As a Spring Quarter requirement, ACCESS students select two of these courses based on their emerging research interests.
Course focuses on situations arising in the laboratory that may present ethical dilemmas for graduate students.
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